QCB News

First QCB Evening – Spring 2025

February 19, 2025

The first QCB Evening for the 2025 Spring semester will be on March 6th (Thursday) from 5:00-6:30PM in SI001. Our two speakers will be Victoria Lopez from the Tracey Lab and Renee Kinne from the Hollenhorst Lab. See our QCB evenings page for more information. Any student from a Trainer lab is welcome to attend!

Scott Publication

February 3, 2025

Liam Scott, a trainee in the Zlotnick lab, has co-authored an ACS Nano study, titled Genetically Engineered Multichromophore Virus-Like Nanoparticles with Ultranarrow Distribution of Emission Intensity. The research, in collaboration with the Dragnea lab (another QCB trainee lab), demonstrates an approach to creating ultra-bright, uniform fluorescent nanoparticles using engineered viral capsid proteins. This work bridges virology, nanotechnology, and advanced imaging techniques, showcasing how viral assembly mechanisms can be repurposed for next-generation optical tools. Congratulations to Liam and the team on this contribution to nanotechnology and synthetic biology!
Figure 1

Bach Publication

January 29, 2025

Andrew Bach (Snaddon Lab), one of our current QCB ambassadors, has co-authored a paper published in Helvetica Chimica Acta. The team developed the first successful construction of quaternary-substituted stereogenic centers using a Lewis base-palladium cooperative catalysis scheme and demonstrated a novel approach to competing with direct deprotonation in chemical reactions. The paper has potential implications for synthesizing complex bioactive molecules and is an important step forward in asymmetric synthesis techniques. Congrats Andrew!

Garrett and Osterberg Publication

December 4, 2024

Two QCB trainees are coauthors on a new paper about how Streptococcus pneumoniae manages zinc toxicity. In the study published in PLOS Pathogens, the team with collaborators at University of Texas Health Science Center discovered that five small regulatory RNAs (Ccn sRNAs) play a crucial role in preventing zinc intoxication in S. pneumoniae. Dr. Abigail Garrett (Winkler lab) is a recently graduated QCB trainee in Microbiology and Maximillian K. Osterberg (Giedroc lab) is a fifth year QCB trainee in Chemistry. Their work helps illuminate how S. pneumoniae, a bacteria responsible for nearly 2 million deaths worldwide each year, oversees metal homeostasis.

Richman Publication

November 28, 2024

Hunter Richman, current QCB trainee, is a co-author on a new paper titled “Targeting the Weak Spot: Preferential Disruption of Bacterial Poles by Janus Nanoparticles” published in Nano Letters. The study, a collaboration between Ying Li’s lab at UW-Madison and QCB training faculty Yan Yu, investigates the interactions between Janus nanoparticles and bacterial cell envelopes, revealing bacterial poles’ curvature as a unique vulnerability to be targeted. Congrats Hunter on your contribution to the field of nanotechnology!

QCB Trainee Seminar

November 21, 2024

Join us tomorrow (Friday November 22nd)  at the Microbiology student seminar series, Microphiles, from 12:40-1:40 in Simon Hall 001 for a talk by QCB Trainee Lauren Augusta from the Fuqua Lab!  Lets show our support and learn more about her research with the crown gall causing bacteria, Agrobacterium tumefaciens.

Lauren Augusta

IU QCB Joins Bluesky

November 20, 2024

You can now follow us on Bluesky at @IUQCB for updates, insights, and community engagement all about QCB!

Laughlin Publication Highlighted in College of Arts + Sciences News

November 18, 2024

QCB trainee, Patrick Laughlin (Zlotnick group), was recently highlighted in IU’s College of Arts + Sciences News for his recent first-author paper in JBC. Patrick’s work has uncovered crucial details about how the COVID-19 virus’s nucleocapsid protein (N-protein) behaves inside infected cells. Congrats Patrick on this well-deserved recognition and we look forward to the continued impact of his research in the field of virology!

Celentano Publication

November 16, 2024

Zach Celentano, a second year Biochemistry PhD student in the van Kessel Lab, recently published a paper titled Quorum sensing in Vibrio controls carbon metabolism to optimize growth in changing environmental conditions in PLOS Biology. These findings provide valuable insights into the evolutionary advantages of quorum sensing, highlighting the role of QS in optimizing gene expression related to methionine and tetrahydrofolate synthesis. Congrats Zach on advancing our understanding of microbial ecology!

Richman Publication

November 11, 2024

Hunter Richman (Yu group) makes contributions to the field of nanomedicine as co-author on a preprint paper published in F1000 Research. The paper, titled Quantitative cytotoxicity analysis of antibacterial Janus nanoparticles in immune and cancer cells, explores the potential of amphiphilic Janus nanoparticles as a promising alternative to traditional antibiotics in combating multi-drug-resistant bacteria. Congrats Hunter!